The thematic groups, as well as specialists, paramedical staff and patient groups work together in two complementary actions:

• The assessment of the available guidelines at the local and national level. Those guidelines are used and highly recommended by ERN-Skin experts.
• The development of ERN-Skin clinical practice guidelines. These guidelines follow the standard evidence-based procedure by involving multidisciplinary group of experts, analyzing literature and taking into account experience of experts, including SKIN ePAG advocates. They are updated every 5 years or before in case of therapeutic innovation.