However, unless new data on these safety issues are made available, the current vaccines should be discussed with caution for patients with a history of serious anaphylactic reaction, it means severe urticaria with angioedema associated with general signs, or even shock, in addition to the need to carry an adrenaline pen.
Here, it must be noted that hereditary angioedema is caused by bradykinin accumulation in tissues, which is not an allergic mechanism. Therefore, there is no contraindication to vaccination for patients suffering from this condition.
Depending on the future availability of other vaccine types, new recommendations will be issued, as necessary.
It must be kept in mind that vaccinated persons must continue to follow the recommended preventive measures against COVID-19, such as wearing a mask, washing regularly hands with soap, practicing social distancing, and others. So far, more information is required to determine whether vaccinated persons can still infect other people that are not immunized against the SARS-CoV2 virus disease.